Small Business Online Advertising,marketing,facebook Fan Pages ...

Tuesday, August 30th, 2011 at 5:33 am ?

Small Business Online Advertising,marketing,facebook Fan Pages

Small commercial operation online promotion

Until recently, online promotion as great as selling as great as selling were something a large firms did. Local commercial operation didn?t see a order for internet publicity, though a times have changed. But now, searches for internal businesses or Small firms have transposed a white as great as a yellow pages. Today, if your internal or internal association is not found upon page a single of a Local Search Engine (SERP), your internal house might not survive.

The role of this essay is to uncover a little of a options upon palm to tiny organisation as great as tiny firms for selling or campaigning online upon a internet. This square of essay will residence sections on; video infomercials, personal ad posting, environment up a Google Places account, producing a website as great as optimizing it for page a single outcome upon a SERP, as great as harnessing a energy of a Social Networks.

Paid Ad Postings

Free as great as paid personal ads posting can be really prolific if finished right or a sum rubbish of time as great as income if not executed in a selling accessible way. The dual many renouned giveaway personal ad sites have been Craig?s List as great as Backpage. Both of these sites will concede content as great as striking advertisements. Because a infancy of internal investiture or internal commercial operation owners do not have an bargain of a html denunciation mandatory to furnish visually delectable ads, a infancy of a advertisements have been really tedious content advertisements. The unhappy partial of this routine is which often, a difference in a ads have been really spider friendly, ensuing in a page a single SERP which should be great, comprehension since when non-stop by a trailblazer they have been presented with tedious text, as great as they rught divided leave a page. Instead of painstakingly celebration of a mass these content ads a presumably spending patron says to heck with it as great as goes to a subsequent SERP outcome but ever anticipating out what we were advertising; a tragedy! These ads intermittently have many if any selling as great as promotion beliefs included in a mailing inside of them such as clickable links to some-more information! This equates to which these ads have been not expected to modify in to sales. Those intensity prospects during once leave but even anticipating out what was there. If personal ads have been rightly placed, there is no doubt which they can as great as do furnish a poignant volume of traffic. It is critical to have your ad mount out by formulating great seeking striking ads with promotion beliefs embedded in to a ads, as great as a call to movement as great as a hyperlink to a owner?s site, or lead constraint or fist page.

Videos have been an additional Search Engine

Did we know which YouTube is a really widespread broadside venue? Video examination is a passion for many. Video is a single of a many appropriate methods for tiny companies as great as tiny businesses to uncover their promotion as great as selling message. Although YouTube is a largest as great as many well-liked video site, it is by distant not a usually video posting site, there have been scores of them; as great as video can be hosted upon your own lay or any alternative hosting site. Video posting sites have been influential, as we can have a video infomercial in mins as great as true divided have it promulgation your special summary 24/7. The successful video collection as great as posting options currently next to or surpass a energy of tall stroke radio advertisings. It is expected to emanate a clickable great seeking striking ad for Craig?s list or Backpage which move people off of those sites to a video using upon your own website, finish with all of a accessible promotion as great as selling beliefs in place! In this approach we have been upon a page which we control, there have been no YouTube competing videos, as great as we can have a lead constraint form as great as alternative promotion element upon which site. A standard Faux clickable ad (embedded formula is not authorised upon Craig?s list or Backpage advertisements) can be had for about 0 as great as it can be used over as great as over again. If we do not have a place to horde a webpage for a video, hosting can be found in a cost operation of per month.

Producing a Small Business Optimized Webpage

SERP optimized web pages have been really dominant, as they expostulate trade to your website for giveaway 24/7. This routine involves a welfare as great as securing of a commercial URL or domain, building a page or mini site as great as optimizing it to be found for specific poke conditions upon a internet. Consultants can publicize scrupulously comparison tall volume rival keywords to land upon page a single of a SERP, which formula in mixed unchanging trade to your website. Please be reminded, which we can optimize your website for a couple of as a single keyword string. Some internal commercial operation as great as internal commercial operation proprietors select to begin with a couple of keywords phrases, as great as enlarge a series of keyword campaigns as their sales intensify.

Google Places is a New Small Business SEO

Google is pulling a Google Places selling to a border of pulling a little preceding page a single SEO keyword phrases to page dual in welfare to Google Places listings. Setting up your Google places comment is so critical which we suggest we to find competent guidance; it will outcome in monetary rewards to you. Google places is so absolute which it can as great as will pull SERP page a single formula over to SERP page dual results; a genocide trap. When your teardrop Google Places idol happens upon page a single of Google, only attend for a receptive to advice of a money register.

Social Networking Yields Local Business Profit

Social media promotion to set up internal friends is quick apropos a mainstream prerequisite for tiny commercial operation owners. Savvy businesses publicize their Facebook as great as Twitter links to capture some-more constant customers. Social media is a latest WEB 2.0, as great as it is starting to pass all alternative promotion venues upon a internet. This theme is so huge, which we only cannot cover it in this article. We will have multiform some-more articles upon this theme to hope for we for a promotion venue of a future.

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Source: http://www.internet-marketingpromotion.org/2011/08/small-business-online-advertisingmarketingfacebook-fan-pages/

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Getting into an Ivy League College; How tough is it?

This article has been viewed 15 times.

If your goal is admission to an Ivy League College, you?ve set the academic bar as high as possible. It?s tougher now to get into Harvard, Yale, etc. now than ever in their histories.

Only five percent of the students admitted to Harvard this year were not in the top 10% of their high school graduating classes. And, many came from very rigorous independent and public high schools?schools with standards well above average.

These students also scored highly on standardized tests, with the middle 50% earning SAT scores of 2080-2370 and/or ACT scores of 31-34. To earn a composite score of 31 on the ACT, by the way, you must answer about 90% of the questions correctly.

But, not only must a student hoping to be admitted to an Ivy compete against incredibly capable students, he/she must compete against lots of them. There were 22,754 applicants to Harvard?s most recent incoming class. Just 2,124 were admitted. You do the math.

Is Harvard tougher to get a ?yes? from than the other Ivy League schools? Perhaps, but not much. So, does anybody really have a decent chance to find himself or herself on an Ivy League campus? Sure, but their numbers are limited.

Start by knowing two realities. One is that are no guarantees you will be admitted no matter how high your grades and test scores are. Ivy League admissions officers will be the first to tell you the sheer number of good applicants force them to turn away thousands of students who would be successful on their campuses.

The second reality is that if you are anywhere near the statistical profile of a student with a chance of admission to an Ivy, you have no reason to feel sorry for yourself. You may not get into an Ivy, but you should have great college choices.

What can you do to improve your chances at the Ivies? You must demonstrate your interest in learning and your intellectual ability with not just good grades, but good grades in the most difficult courses available to you. If the possibilities at your high school are limited, consider enrolling in a few courses at a local college.

Take both the ACT and SAT early. Analyze the results and determine where you need to improve. Then, get to work. Do it in a test prep course, by yourself (with professionally prepared materials) or with a tutor?preferably one with test prep experience.

Make yourself what used to be called a ?well rounded? person; it?s good for you and good for your candidacy. Join clubs or organizations in which you have genuine interest. I repeat, genuine interest. Accept positions of leadership if they are available.

As difficult and stressful as essays may be, they give you a chance to be viewed as a whole person, not just another faceless high-achiever. You need to do your best thinking and best writing. And, ask at least two adults in whom you have great trust (perhaps a teacher or counselor among them) to review your final draft.

Consider early decision or a similar program if it is available to you. Such options can improve your chances, but they may not make sense for everyone.

You will be asked for two or three references. Choose them carefully?very carefully. A single luke warm or negative comment on a recommendation may be damaging.

Take advantage of the personal growth opportunities available to you. And, spend some ongoing time helping others. You?ll be a better person. And you might pick up some good kharma. You need every edge you can get, right?

Remember that the Ivies want academically motivated, capable, high potential students; students who will do well in college and beyond. They also seek diversity, and students who can and will contribute to the college community because of their leadership skills, special interests, and/or talents.

Daniel Z. Kane has had a long career in education. His many educational websites deal with subjects such as online college degrees , online and distance education , and adult education online.

Source: http://canarymagazine.net/education/college-education/getting-into-an-ivy-league-college-how-tough-is-it/

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Tibet monk given 11 yrs in colleague's immolation (AP)

BEIJING ? A Chinese court sentenced a Tibetan Buddhist monk to 11 years in jail Monday after ruling he hid another monk who set himself on fire, thereby preventing him from receiving emergency treatment.

The official Xinhua News Agency said the court in Sichuan province's Aba prefecture imposed the sentence on Drongdru after a one-day trial.

It convicted Drongdru, a monk in the Kirti monastery, on charges of intentional homicide for hiding another monk, Rigzin Phuntsog, for 11 hours after he set himself on fire.

Xinhua said Phuntsog, 16, was a nephew and a disciple of Drongdru and that he died even though he eventually received treatment in a hospital.

The March 16 death of Phuntsog was seen as a protest against China's heavy-handed controls on Tibetan Buddhism and provoked a standoff between security forces and monks.

Aba prefecture has been the scene of numerous protests over the past several years against the Chinese government.

A second trial will be held Tuesday in which monks Tsering Tenzin and Tenchum will face charges of plotting, instigating, and assisting in the self-immolation, said a clerk with the Maerkang County People's Court in Aba who gave only his surname, Zhou.

Kirti monastery is under tight guard by security forces who have been accused by overseas pro-Tibetan groups of beating onlookers and detaining monks. The area is off-limits to foreign journalists.

The circumstances surrounding the monk's death remain murky. In June, China rejected pressure from a U.N. human rights panel to provide information about more than 300 monks from Kirti whose whereabouts it said are unknown since the monastery was raided in April.

The Foreign Ministry said only that monks were undergoing "legal education" ? a reference to compulsory political lectures on the basics of the Chinese Constitution, criminal law and regulations on religious affairs.

Tibetan monks tend to be fiercely loyal to Tibet's exiled Buddhist leader, the Dalai Lama, who is reviled by Beijing. As custodians of Tibet's Buddhist culture, they tend to be especially concerned about tight Chinese controls over monasteries that take time away from religious study and practice.

Source: http://us.rd.yahoo.com/dailynews/rss/china/*http%3A//news.yahoo.com/s/ap/20110829/ap_on_re_as/as_china_monk_dies

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Doctors misuse scans in prostate cancer: study (Reuters) | News Bay

NEW YORK (Reuters Health) ? Too many men with low- or medium-risk prostate cancer get CTs and bone scans that aren?t recommended for them, suggests a new study.

The scans are intended to tell doctors if cancer has spread beyond the prostate in men with high-risk cancer.

Doing them in other cases is a concern because CTs expose patients to small amounts of radiation ? which itself is linked to future cancer risks ? and the scans cost the healthcare system extra money, but have little potential benefit.

The research also suggests that not enough men with high-risk cancer get the scans, which means some of them may get treatment for local (confined to the prostate) cancer that?s unlikely to help if the cancer has spread.

?In high-risk patients, those are the ones that have a high risk of positive lymph nodes or (cancer that has) spread to the bone,? said Dr. David Samadi, a prostate cancer surgeon at the Mount Sinai Medical Center in New York who was not involved in the new study.

?Otherwise for low-risk disease, the likelihood of finding a positive bone scan or CT scan is low,? he told Reuters Health.

Guidelines from the American Urological Association say that doctors should use other measures such as prostate-specific antigen (PSA) testing to determine a man?s risk of advanced cancer and then only scan those with high-risk disease to determine the best treatment.

Researchers led by Dr. Jim Hu of Brigham and Women?s Hospital in Boston wanted to see how frequently those recommendations were being followed.

They consulted a database of U.S. men covered by Medicare who were diagnosed with prostate cancer in 2004 and 2005 ? a total of 30,000 cases.

Both bone scans and CTs were more common in men who were diagnosed with high-risk cancer.

Sixty percent of those men had one of the scans. Still, one-third of men with low-risk cancer and almost half of those with medium-risk cancer had a scan in between diagnosis and treatment.

Hu and colleagues calculated that the cost of unnecessary scans in men with low- and medium-risk cancer billed to Medicare during those two years was about $3.6 million for their study group. (The government-run insurance program paid an average of $226 for each bone scan and $407 for a CT).

Extra scanning not recommended by guidelines ?significantly increases Medicare expenditure without improving quality of care rendered for men with newly diagnosed prostate cancer,? the authors wrote in the journal Cancer.

And each extra CT scan exposes men to a small amount of radiation, while also providing an opportunity for doctors to catch something ?incidental? that may not pose a threat but still leads to more testing or procedures, Samadi said.

Another recent study found that coaching and feedback from peers about the proper use of the tests helped prostate surgeons reduce the number of unnecessary scans they ordered. Samadi thinks many doctors are just trying to be on the safe side by ordering more tests.

?A lot of it has to do with the fact that most urologists when they think of prostate cancer it?s almost like a knee-jerk reaction ? automatically they think bone scan and CT scan,? Samadi said.

The researchers noted that finding four in 10 men with high-risk cancer aren?t getting a scan is also ?worrisome.?

If doctors don?t recognize that cancer has spread in some of those men, they said, they won?t benefit from treatment directed just at the prostate.

SOURCE: http://bit.ly/pYwBrh Cancer, online August 5, 2011.

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Doctors misuse scans in prostate cancer: study
(Reuters)

Posted by News Bay on Aug 26th, 2011 and filed under Health. You can follow any responses to this entry through the RSS 2.0. Both comments and pings are currently closed.

Source: http://www.newsbay.info/doctors-misuse-scans-in-prostate-cancer-study-reuters/

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Research in Motion (Investor's Business Daily)

Research in Motion (NASDAQ:RIMM - News) was raised to buy by Sterne Agee, which expects the BlackBerry maker to gain from its new smartphones that feature the Blackberry 7 operating system. The analyst also said carriers want a viable option other than Apple's (NASDAQ:AAPL - News) iPhone and handsets using Google's (NASDAQ:GOOG - News) Android software. The other top contender to be the 3rd long-term smartphone contender: Nokia (NYSE:NOK - News), with its Microsoft (NASDAQ:MSFT - News) Windows Mobile alliance. RIM shares rose 3.4% to 29.18.

Source: http://us.rd.yahoo.com/dailynews/rss/applecomputer/*http%3A//news.yahoo.com/s/ibd/20110826/bs_ibd_ibd/582988

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Earning through Affiliate Advertising Companies - ad revenue 09,10 ...

Earning through Affiliate Advertising Companies

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Earning through Affiliate Advertising Companies

Posted: Apr 27, 2011 |Comments:
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The advent of Affiliate advertising companies has created sufficient space for alternate as well as traditional forms of advertising. This is a welcome situation considering the status of the global advertising industry. The emergence of the internet as a major source of communication has made many affiliate advertisers and companies to choose this medium over others to post information or conduct business transactions. With more and more customers using the internet to shop around for any product or service, the role of affiliate advertising companies has become very important. Affiliate advertising offers a great opportunity for many online entrepreneurs to make money working from home.

The Role of Affiliate Advertisers and Online Marketers

The role of online marketers and affiliate advertisers are quite similar since they have more or less similar responsibilities. In fact affiliate advertising brings both of them much closer. This is precisely the reason as to why most website owners, online publishers and advertisers prefer affiliate advertising programs as an effective way of earning money from home. In fact this is a specialized marketing technique use by many advertisers to post ads in the form of icons and click them on, all within a given online site. Take for instance an advertising company that launches an advertising campaign on the internet. Such a company would get into a lot of agreements with other websites on the internet in order to place its ads strategically on their websites. The website owners are motivated to be a part of the advertising campaign through commissions or incentives.

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Endless Opportunities for Website Owners

Affiliate advertising companies offer a tremendous opportunity for the website owners. As long as there is a continuous flow of customer traffic to the site, there is always a possibility of customers clicking on the ads placed by the advertiser. This helps the website owners to earn handsomely just by taking care of their websites.

Redefining Online Advertising

Affiliate advertising companies have redefined the way ads are placed on line. This technique has ensured that both advertisers as well as the website owners gain and benefit. Even the consumers stand to gain because they get redirected to sites containing products and services that they want to buy.?

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About the Author:

Jon Smith is a very popular writer associated with revenuestreet.com.Revenuestreet is the leading real results Online Ads Company and Online Affiliate Company That provides globally recognized, full service capability in a performance based driven model.

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The Pros and Cons of Big and Small Advertising Companies

Nina DiSesa, chairman of McCann Erickson New York, talks about whether it?s better to choose a big advertising company or a small advertising company. She also discusses the pros and cons of both type of companies. (02:25)

Peer39?s Amiad Solomon on Contextual Advertising Growth in the Downturn

Offline advertising may be hurting, but at the AlwaysOn conference last week, online advertisers?especially those with performance-based models?were still reporting positive growth, including semantic advertising company Peer39, one of the OnMedia 100. Peer39?s technology reads the context of an entire page rather than individual words to deliver accurately targeted advertising. The company acquired the inventors of Google AdSense and talent from Tacoda for their team. (02:59)

Mixpo Expands Online Video Platform to Advertising Agencies

Mixpo, the Seattle-based company which integrates local television advertising into local websites, is now offering its platform to advertising agencies, the company announced today. We spoke with CEO Anupam Gupta last week here in New New York. (05:39)

Chris Hock on BlackArrow?s Advertising in Video on Demand

As time-shifting viewing habits of cable TV by consumers increases, there is a big challenge to the cable operators and programmers how to insert relevant advertising in to the programming. BlackArrow, a San Mateo-based company, apparently has a solution. The company has been heavily funded by some key strategic investors including Cisco, Comcast, Intel and top VC?s Mayfield and Polaris. VP Chris Hock has more. (04:52)

Boston Video SEO Company Sets to Be Next Google AdSense

White label video SEO service EveryZing is working to reinvent video advertising the same way Google AdSense reinvented text advertising, CEO Tom Wilde told Beet.TV. (04:43)

?Content is king?, but the fundamentals matter as well. Here are three rudiments lots of CPA websites overlook.

By:
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Aug 26, 2011

The commercial capital of India is forever expanding, and with more and more big brands and multinationals heading for Mumbai, this trend is will only witness better times ahead. Commercial offices in Andheri, Worli, Powai, etc

By:
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l
Aug 25, 2011

A solid marketing foundation is key to a solid business. Even the big boys like Pepsi and Coke realize this! If they get comfortable and let their marketing efforts relax, then sales will suffer, and they?ll have to work twice as hard to get back their share of the market. You, as an entrepreneur and master of your own domain, have to be cognizant of where you spend your time and dollars. Just like a house, you need a strong foundation that you can build on that will stand the test of time.

By:
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Aug 25, 2011

A brand?s positioning encapsulates the brand?s core values and its very purpose for existence; it is that one snapshot which emanates in your mind when you think of a brand and if it is communicated effectively, a strong association is built between the brand and its positioning.

By:
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l
Aug 25, 2011

Have you ever felt strange about marketing your services for fear of people thinking you weren?t successful enough or good enough at what you do? I was reading a transcript of marketer Dan Kennedy?s Coaching and Consulting Business Boot Camp this past week at the beach and I came across a section about the fine line between the need for marketing and not wanting to look like you NEED business.

By:
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l
Aug 25, 2011

A large number of people due to laziness and lack of physical activity accumulate a huge layer of fat around their abdominal section. There can also be other reasons behind this fat accumulation such as stress and overeating. If you too are suffering from excessive belly fat, don?t worry just act.

By:
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Aug 25, 2011

Nowadays the most important question arising in every person?s mind is how to get a flat stomach. The answer is quite simple. In every workout regime which is aimed at reducing excessive body weight, getting a flat stomach is the toughest part. You can tone up your whole body very quickly but the abdominal part takes some longer time to react and show desirable result.

By:
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Aug 24, 2011

Market is flooded with a large number of medicines, and exercising equipment that guarantees six pack abs with in shortest period of time. Every product boasts of its superiority and efficiency over other. But the most important truth about abs formation is very simple.

By:
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Aug 24, 2011

There are many six pack abs workout programs available in the market. These entire six pack abs workout regime insures six pack abs in the shortest possible time. So here I am going to tell you something about these six pack abs workout programs available in the market that guarantee you best results.

By:
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Aug 19, 2011

Everyone has a key ring. We wouldn?t be able to lead an organized life if we had loose keys lying all over the place. So we have separate key rings for different keys for the house, the car, the wardrobes etc. Key rings and Key Fobs though perform another key role other than organising our keys for us.

By:
l
l
Aug 17, 2011

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Sheriff's raid on Days Inn in Phoenix nets 1 identity theft arrest

by Carly M. Price - Aug. 24, 2011 12:05 PM
The Arizona Republic-12 News Breaking News Team

The Maricopa County Sheriff's Office raided a Days Inn hotel in Phoenix, trying to arrest 10 employees on suspicion of identity theft and being in the country illegally.

Deputies arrested one woman at the hotel at Seventh Avenue and Camelback Road on Wednesday morning, but officials said the other nine had not shown up to work.

Maricopa County Sheriff Joe Arpaio said his office had identified three out-of-state residents whose identities were used by the employees.

Arpaio said the general manager had recently switched the schedule "because of the economy," so the employees were expected to clock in at 10 a.m., two hours later than usual.

Arpaio credited an unnamed source for the "great record keeping" and a "well-documented" report that allowed the MCSO to complete the raid in two months. He said it normally takes six months to investigate such cases.

The next move for the Sheriff's Office is to seek out the remaining nine to serve warrants for their arrests in connection with identity theft and illegal immigration.

The sheriff said those arrested will likely face charges of identity theft before an investigation about their legal status. The raid is the 51st such operation this year.

Source: http://www.azcentral.com/community/phoenix/articles/2011/08/24/20110824phoenix-sheriff-joe-arpaio-raid-days-inn-abrk.html

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Top 52 fastest-growing real estate companies

Image courtesy of Bo47.

The lastest Inc. magazine list of the 5,000 fastest-growing private companies in the U.S., released this week, includes 52 companies in its real estate category.

Companies on the Inc. 5000 are ranked by overall revenue growth in the three-year period between 2007-10.?In order to qualify, companies had to have generated revenue by March 31, 2007; have generated at least $100,000 in revenue in 2007, and at least $2 million in revenue in 2010; and be privately held, for profit, based in the U.S., and independent?(not a subsidiary or division of another company), according to the Inc. website.?

Marietta, Ga.-based appraisal management company Valuation Management Group was at the top of the list of companies in the real estate category, with a 7,910 percent jump in revenue growth, to $25.4 million in 2010. The company had 50 employees at the end of 2010, up from three at the end of 2007. The company ranked at No. 22 in the overall list of 5,000 companies.

Oklahoma City-based Pointe Vista Development, a planned residential community in development on Lake Texoma, ranked second among real estate companies. The company saw a 3,068 percent jump in revenue from 2007, to $3.8 million in 2010. The company grew from one employee in 2007 to 60 in 2010.

Golden Valley, Minn.-based property management firm Renters Warehouse was third in the real estate category. The company?s revenue grew 2,085 percent from 2007, to $3.3 million in 2010. The company grew from four employees in 2007 to 39 in 2010.

Ranking fourth among real estate companies was real estate brokerage company PalmerHouse Properties, based in Atlanta. The company?s revenue grew 1,726 percent from 2007, to $2.3 million in 2010. The company grew from 27 employees in 2007 to 535 in 2010.

Potomac, Md.-based Innotion Enterprises, which provides technology, management, and marketing services to asset managers for real estate owned properties, ranked fifth among companies in the real estate category. That company?s revenue jumped 1,564 percent from 2007, to $14.4 million in 2010. The company had 46 employees in 2010, up from six in 2007.

Other notables on the list of 52 real estate companies:

• Henderson, Nev.-based real estate brokerage and property management firm Realty One Group ranked 17th with a 410 percent jump in revenue between 2007 and 2010, to $2.1 billion ? by far the highest revenue total on the list. The company grew from 22 employees in 2007 to 58 in 2010.
• Seattle-based property search and valuation site Zillow ranked 20th on the list. The company saw a 329 percent increase in revenue between 2007 and 2010, to $30.5 million. The company had 252 employees in 2010; no comparable figure was listed for 2007.

Following is a list of the 52 real estate category companies:

RANK COMPANY NAME 3-YEAR % REVENUE GROWTH 2010 REVENUE? STATE 22 Valuation Management Group 7910% $25.4 million GA 75 Pointe Vista Development 3068% $3.8 million OK 132 Renters Warehouse 2085% $3.3 million MN 172 PalmerHouse Properties 1726% $2.3 million GA 194 Innotion Enterprises 1564% $14.4 million MD 222 US Appraisal Group 1432% $3 million IL 257 Real Property Management 1252% $11.4 million UT 284 Campus Habitat 1149% $16.5 million NY 337 The Menkiti Group 988% $5.2 million DC 344 PayLease 974% $4.8 million CA 398 Fairplay Financial 857% $3.1 million WA 408 Maximum One Realty Greater Atlanta 834% $4.1 million GA 530 Movoto.com 637% $3.4 million CA 586 Property Solutions 560% $11.1 million UT 667 RedVision Systems 477% $42.8 million NJ 723 rentbits.com 435% $2.6 million CO 765 Realty ONE Group 410% $2.1 billion NV 798 A2Z Field Services 392% $16.8 million OH 883 Gorilla Capital 348% $36.4 million OR 930 Zillow 329% $30.5 million WA 1097 Pro Teck Services 275% $40.8 million MA 1101 Global DMS 273% $2.7 million PA 1153 Accurate Group 257% $16.6 million NC 1202 Direct Title Solutions 245% $2.2 million VA 1215 eMortgage Logic 242% $63.8 million TX 1252 Thomas Title Escrow 233% $3.3 million AZ 1253 Linear Title Closing 233% $17.9 million RI 1268 PropertyRate 230% $2.2 million CA 1743 Active Website 153% $3.4 million CO 1986 Keller Williams Capital Properties 128% $9.2 million DC 2016 Bean Group 126% $9.5 million NH 2121 Asset Plus Companies 118% $12.5 million TX 2162 Mainstreet Property Group 115% $9.6 million IN 2165 NitNeil Partners 115% $4.3 million GA 2315 Occidental Management 105% $5.5 million KS 2635 SingleSource Property Solutions 88% $35.1 million PA 2714 4Corners Homes 83% $20.8 million OK 2747 Conservice 81% $20.9 million UT 3026 Benham Real Estate Group 67% $40.5 million NC 3081 Best Facility Services 65% $4.7 million TX 3119 Temporary Housing Directory 64% $33.2 million TX 3263 American Reporting 58% $8.2 million WA 3267 Ohio Realty Advisors 58% $3 million OH 3574 Chicago Apartment Finders 47% $8.6 million IL 4001 reQuire Release Tracking 32% $5.3 million VA 4009 Merrill Gardens 32% $217 million WA 4158 ERA Sunrise Realty 27% $6.9 million GA 4633 Prometheus Real Estate Group 14% $368.6 million CA 4691 Broad Street 12% $25.8 million MD 4702 Housing Helpers 12% $4.2 million CO 4769 REO Allegiance 10% $6.6 million NJ 4856 Integra Realty Resources 7% $104.1 million NY

Source: Inc.

Though not included in the real estate category, other real estate-related companies were included among the overall list of 5,000. Among these was BoomTown, a real estate marketing software company, and Realeflow, a company that provides real estate entrepreneurs and investors with business management software. Both companies were ranked in the software category.

Boomtown ranked at No. 174 in the overall list of 5,000 and No. 18 in the software category. The company?s revenue grew 1,712 percent between 2007 and 2010, to $2.2 million. The company grew from three employees in 2007 to 19 employees in 2010.

Realeflow ranked at No. 421 among the Inc. 5000 and No. 43 in the software category. The company?s revenue jumped 828 percent from 2007, to $6 million in 2010. The company had 31 employees at the end of 2010, up from six at the end of 2007.

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Source: http://columbia-mo.net/2011/08/25/top-52-fastest-growing-real-estate-companies/

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Researchers find 'key' used by ebola virus to unlock cells and spread deadly infection

Public release date: 24-Aug-2011
[ | E-mail | Share ]

Contact: Kimberly Newman
sciencenews@einstein.yu.edu
718-430-3101
Albert Einstein College of Medicine

Findings published in Nature could lead to drugs that thwart outbreaks

August 24, 2011 (Bronx, NY) Researchers at Albert Einstein College of Medicine of Yeshiva University (http://www.einstein.yu.edu/home/default.asp) have helped identify a cellular protein that is critical for infection by the deadly Ebola virus. The findings, published in today's online edition of Nature, suggest a possible strategy for blocking infection due to Ebola virus, one of the world's most lethal viruses and a potential bioterrorism agent.

The study was a collaborative effort involving scientists from Einstein, the Whitehead Institute for Biomedical Research, Harvard Medical School, and the U.S. Army Medical Research Institute of Infectious Diseases.

Ebola virus is notorious for killing up to 90 percent of the people it infects. Ebola hemorrhagic fever the severe, usually fatal disease that Ebola virus causes in humans and in nonhuman primates first emerged in 1976 in villages along the Ebola River in the Sudan and the Democratic Republic of the Congo, Africa. Since then, about two dozen outbreaks have occurred.

Though Ebola and Marburg hemorrhagic fevers are fortunately rare diseases, "even small outbreaks of Ebola or Marburg virus can cause fear and panic," said co-senior author (http://www.chandranlab.org/) Kartik Chandran, Ph.D., assistant professor of (http://www.einstein.yu.edu/microbio/home.aspx) microbiology & immunology at Einstein "And then there's the worry that these viruses could be used for bioterrorism."

Ebola virus's ability to enter cells is reminiscent of the Trojan Horse used by the ancient Greeks to defeat their archenemies. Ebola virus binds to the host cell's outer membrane, and a portion of host cell membrane then surrounds the virus and pinches off, creating an endosome a membrane-bound bubble inside the cell (see image). Endosomes carry their viral stowaways deep within the cell and eventually mature into lysosomes tiny enzyme-filled structures that digest and recycle cellular debris.

The viruses captive in the lysosome manage to escape destruction by exploiting components of the cell to gain entry to the cytoplasm, the substance between the cell membrane and the nucleus where the virus can replicate. But the identities of many of these components have remained unknown.

In seeking the answer, Einstein researchers and colleagues searched for proteins that Ebola virus might exploit to enter the cell's cytoplasm. One such cellular protein, known as Niemann-Pick C1 (NPC1), stood out.

"We found that if your cells don't make this protein, they cannot be infected by Ebola virus," said Dr. Chandran. "Obviously it's very early days, but we think our discovery has created a real therapeutic opportunity." At present, there are no drugs available to treat people who have been infected with Ebola virus or approved vaccines to prevent illness."

The NPC1 protein is embedded within cell membranes, where it helps transport cholesterol within the cell. However, the absence of NPC1 due to gene mutations causes a rare degenerative disorder called Niemann-Pick disease, in which cells become clogged up with cholesterol and eventually die.

To confirm their finding that NPC1 is crucial for Ebola virus infection, the researchers challenged mice carrying a mutation in NPC1 with Ebola virus. Remarkably, most of these mutant mice survived the challenge with this normally deadly virus. Similarly, fibroblast cells (found in connective tissue) from people with Niemann-Pick disease were resistant to Ebola virus infection, as were human cells from other organs that were manipulated to reduce the amount of NPC1 they contained.

The researchers also tested whether other major viruses need NPC1 to infect human cells. Only Ebola virus and its close relative, Marburg virus, were found to require the presence of NPC1 protein for infection. Like Ebola virus, Marburg virus also needs NPC1 to kill mice.

"Our work suggests that these viruses need NPC1, which is embedded in the lysosomal membrane, to escape from the lysosome into the cytoplasm," said Dr. Chandran. "We are now testing that hypothesis in the laboratory."

The discovery of NPC1's crucial role in Ebola infection raises the possibility that Ebola and Marburg virus outbreaks could be thwarted by a drug that blocks the action of NPC1. "Even though such a treatment would also block the cholesterol transport pathway, we think it would be tolerable," said Dr. Chandran. "Most outbreaks are short-lived, so treatment would be needed for only a short time." Einstein, in conjunction with the Whitehead Institute of Biomedical Research and Harvard Medical School, has filed a patent application related to this research that is available for licensing to partners interested in further developing and commercializing this technology.

Remarkably, an anti-Ebola virus inhibitor Dr. Chandran found as a postdoctoral fellow at the Brigham and Women's Hospital in Boston, MA turns out to be just such an NPC1 blocker, as described in a separate manuscript by Marceline Ct and co-workers to be published in the same issue of Nature.

###

The main paper is entitled "Ebola virus entry requires the cholesterol transporter Niemann-Pick C1." Other authors include Anthony Wong, Ph.D., and Nirupama Mulherkar, Ph.D., at Einstein; Sean P. Whelan, Ph.D., Matthijs Raaben, Ph.D., Philip J. Kranzusch, and April M. Griffin of Harvard, Boston, MA; Thijn R. Brummelkamp, Ph.D., and Gregor Obernosterer of the Whitehead Institute and the Netherlands Cancer Institute, Amsterdam, The Netherlands; Jan E. Carette, Ph.D., of the Whitehead Institute, Cambridge, MA, and Stanford University School of Medicine, Stanford, CA; John M. Dye, Ph.D., Andrew S. Herbert, Ph.D., Ana I. Kuehne, and Gordon Ruthel of the U.S. Army, Fort Detrick, MD; and Paola Dal Ci, Ph.D., of the Center for Advanced Molecular Diagnostics, Boston, MA.

This research was supported by grants from the National Institute of Allergy and Infectious Diseases and the National Human Genome Research Institute, both part of the National Institutes of Health; the U.S. Army; and the Burroughs Wellcome Fund.

Albert Einstein College of Medicine Albert Einstein College of Medicine of Yeshiva University is one of the nation's premier centers for research, medical education and clinical investigation. In 2010, Einstein received nearly $200 million in support from the NIH for major ( http://www.einstein.yu.edu/home/nih.asp) research centers at Einstein in diabetes, cancer, liver disease, and AIDS, as well as other areas. Through its extensive affiliation network with five medical centers, Einstein runs one of the largest post-graduate medical training programs in the United States, offering approximately 150 residency programs to more than 2,500 physicians in training. For more information, please visit www.einstein.yu.edu

---

[ | E-mail | Share ]

?

AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.

Public release date: 24-Aug-2011
[ | E-mail | Share ]

Contact: Kimberly Newman
sciencenews@einstein.yu.edu
718-430-3101
Albert Einstein College of Medicine

Findings published in Nature could lead to drugs that thwart outbreaks

August 24, 2011 (Bronx, NY) Researchers at Albert Einstein College of Medicine of Yeshiva University (http://www.einstein.yu.edu/home/default.asp) have helped identify a cellular protein that is critical for infection by the deadly Ebola virus. The findings, published in today's online edition of Nature, suggest a possible strategy for blocking infection due to Ebola virus, one of the world's most lethal viruses and a potential bioterrorism agent.

The study was a collaborative effort involving scientists from Einstein, the Whitehead Institute for Biomedical Research, Harvard Medical School, and the U.S. Army Medical Research Institute of Infectious Diseases.

Ebola virus is notorious for killing up to 90 percent of the people it infects. Ebola hemorrhagic fever the severe, usually fatal disease that Ebola virus causes in humans and in nonhuman primates first emerged in 1976 in villages along the Ebola River in the Sudan and the Democratic Republic of the Congo, Africa. Since then, about two dozen outbreaks have occurred.

Though Ebola and Marburg hemorrhagic fevers are fortunately rare diseases, "even small outbreaks of Ebola or Marburg virus can cause fear and panic," said co-senior author (http://www.chandranlab.org/) Kartik Chandran, Ph.D., assistant professor of (http://www.einstein.yu.edu/microbio/home.aspx) microbiology & immunology at Einstein "And then there's the worry that these viruses could be used for bioterrorism."

Ebola virus's ability to enter cells is reminiscent of the Trojan Horse used by the ancient Greeks to defeat their archenemies. Ebola virus binds to the host cell's outer membrane, and a portion of host cell membrane then surrounds the virus and pinches off, creating an endosome a membrane-bound bubble inside the cell (see image). Endosomes carry their viral stowaways deep within the cell and eventually mature into lysosomes tiny enzyme-filled structures that digest and recycle cellular debris.

The viruses captive in the lysosome manage to escape destruction by exploiting components of the cell to gain entry to the cytoplasm, the substance between the cell membrane and the nucleus where the virus can replicate. But the identities of many of these components have remained unknown.

In seeking the answer, Einstein researchers and colleagues searched for proteins that Ebola virus might exploit to enter the cell's cytoplasm. One such cellular protein, known as Niemann-Pick C1 (NPC1), stood out.

"We found that if your cells don't make this protein, they cannot be infected by Ebola virus," said Dr. Chandran. "Obviously it's very early days, but we think our discovery has created a real therapeutic opportunity." At present, there are no drugs available to treat people who have been infected with Ebola virus or approved vaccines to prevent illness."

The NPC1 protein is embedded within cell membranes, where it helps transport cholesterol within the cell. However, the absence of NPC1 due to gene mutations causes a rare degenerative disorder called Niemann-Pick disease, in which cells become clogged up with cholesterol and eventually die.

To confirm their finding that NPC1 is crucial for Ebola virus infection, the researchers challenged mice carrying a mutation in NPC1 with Ebola virus. Remarkably, most of these mutant mice survived the challenge with this normally deadly virus. Similarly, fibroblast cells (found in connective tissue) from people with Niemann-Pick disease were resistant to Ebola virus infection, as were human cells from other organs that were manipulated to reduce the amount of NPC1 they contained.

The researchers also tested whether other major viruses need NPC1 to infect human cells. Only Ebola virus and its close relative, Marburg virus, were found to require the presence of NPC1 protein for infection. Like Ebola virus, Marburg virus also needs NPC1 to kill mice.

"Our work suggests that these viruses need NPC1, which is embedded in the lysosomal membrane, to escape from the lysosome into the cytoplasm," said Dr. Chandran. "We are now testing that hypothesis in the laboratory."

The discovery of NPC1's crucial role in Ebola infection raises the possibility that Ebola and Marburg virus outbreaks could be thwarted by a drug that blocks the action of NPC1. "Even though such a treatment would also block the cholesterol transport pathway, we think it would be tolerable," said Dr. Chandran. "Most outbreaks are short-lived, so treatment would be needed for only a short time." Einstein, in conjunction with the Whitehead Institute of Biomedical Research and Harvard Medical School, has filed a patent application related to this research that is available for licensing to partners interested in further developing and commercializing this technology.

Remarkably, an anti-Ebola virus inhibitor Dr. Chandran found as a postdoctoral fellow at the Brigham and Women's Hospital in Boston, MA turns out to be just such an NPC1 blocker, as described in a separate manuscript by Marceline Ct and co-workers to be published in the same issue of Nature.

###

The main paper is entitled "Ebola virus entry requires the cholesterol transporter Niemann-Pick C1." Other authors include Anthony Wong, Ph.D., and Nirupama Mulherkar, Ph.D., at Einstein; Sean P. Whelan, Ph.D., Matthijs Raaben, Ph.D., Philip J. Kranzusch, and April M. Griffin of Harvard, Boston, MA; Thijn R. Brummelkamp, Ph.D., and Gregor Obernosterer of the Whitehead Institute and the Netherlands Cancer Institute, Amsterdam, The Netherlands; Jan E. Carette, Ph.D., of the Whitehead Institute, Cambridge, MA, and Stanford University School of Medicine, Stanford, CA; John M. Dye, Ph.D., Andrew S. Herbert, Ph.D., Ana I. Kuehne, and Gordon Ruthel of the U.S. Army, Fort Detrick, MD; and Paola Dal Ci, Ph.D., of the Center for Advanced Molecular Diagnostics, Boston, MA.

This research was supported by grants from the National Institute of Allergy and Infectious Diseases and the National Human Genome Research Institute, both part of the National Institutes of Health; the U.S. Army; and the Burroughs Wellcome Fund.

Albert Einstein College of Medicine Albert Einstein College of Medicine of Yeshiva University is one of the nation's premier centers for research, medical education and clinical investigation. In 2010, Einstein received nearly $200 million in support from the NIH for major ( http://www.einstein.yu.edu/home/nih.asp) research centers at Einstein in diabetes, cancer, liver disease, and AIDS, as well as other areas. Through its extensive affiliation network with five medical centers, Einstein runs one of the largest post-graduate medical training programs in the United States, offering approximately 150 residency programs to more than 2,500 physicians in training. For more information, please visit www.einstein.yu.edu

---

[ | E-mail | Share ]

?

AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.

Source: http://www.eurekalert.org/pub_releases/2011-08/aeco-rf082211.php

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4 Tips For Holiday Eating | Anti Aging Tips

This is a gift exchange we have our dear friend, spread the good word of the Lord Jesus Christ was born, the time of the year. Christmas has arrived, both held anywhere. Different types of food served during the party. Of course more than indulge in their food and drink, nothing.

But mostly because of high fat and cholesterol provide food, we need to be careful what we eat. Alcoholic beverages, causing damage much pleasure if not you take the appropriate measures. Although it might not be feeling this season, next month will be smaller size jeans, February 12.

Party food and drink, most of your excess belly fat, he was a main contributor. It is best, the process must be implemented to all parties in the regulation of food intake. Although it can be eaten, it could not get the good advice of my things. The main component of alcoholic beverages, the party begins. It is more relaxed, outgoing feel. Entertainment, we are very easy when you have some wine. However, there is always some words to remember. Close these drinks too much, could damage our bodies. Ulcers, liver damage and kidney failure side effects.

Here are some tips to keep yourself healthy during the Christmas season. Thus, we can enjoy the party, you can use our healthcare.

O Please avoid high-fat foods. It is best to avoid such foods. It's really unavoidable, eat a little bit.

? The drink plenty of water. The water will feel full. In this way, lose your appetite '.

Limit your drinking as much as possible ?. Excesses Don 'T. The only possible if you have a champagne glass, don 'T below, please try to move people to the party. Drink only bring more harm than good for you.

Practice ?, free 're time. If you try to lose some weight, get one from the past.

Some of these holiday tips. This is a good thing, indulge in a celebration of self, "Do not forget that our health. Merry Christmas.

Source: http://www.antiaging123.info/4-tips-for-holiday-eating/

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Disrupt SF Hackathon Registration Now Open! Plus Last Day for Early Bird Tickets

Registration is officially open for our fourth Hackathon, and we'd love to make it our biggest yet! We promise more pizza, more caffeine and more glory than ever. We had 700 registrants for the last event in New York -- let's top it! The format remains the same - a little less than 24 hours to create a hack on site and present a working demo to an audience of developers, press and industry insiders. Sign up now! Celebrating Developers GroupMe has proven that you can build a Weekend-hacked, Seed-funded, Series-A-ed, Acquired-by-Skype, all-in-about-a-year startup from a TC Hackathon. (Props to Jared and Steve's for their monstrous hustle). But the goal of these increasingly awesome events isn't just to build startups--we want to give developers a platform to shine. For every GroupMe there's a Mr Stabbyphone; for every Wisedame there's a Drunkerator; for every Docracy a Venture Crapital. It's that mixture of utility and whimsy that keeps the Hackathons, and our industry for that matter, fresh. Much of the field is built behind the scenes by the hard work of talented developers and Hackathons are a the best way we've found to spotlight them.

Source: http://feedproxy.google.com/~r/Techcrunch/~3/BX5GcRbc6NA/

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How to Cope Food Allergies - Lexuss Health Site

August 22nd, 2011 by admin

How To Cope With Food Allergies ? The best home videos are here

This video will give you tips on how to cope with your food allergies. A food allergy is an adverse immune response to a food protein. They are distinct from other adverse responses to food, such as food intolerance, pharmacological reactions, and toxin-mediated reactions. A protein in the food is the most common allergic component. This video gives some steps on how to cope up with this allergy problem.

Posted in Health and Fitness | | Comments Off

Sorry, the comment form is closed at this time.

Source: http://www.lexuss.info/health-and-fitness/how-to-cope-food-allergies/

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Members of Gaming Communities Are the Best Video Game Designers ...

Video Or Desktop computer Gaming Software Companies Am confident that Who seem to Ones crucial Guardians In addition , Followers are, Because do not need to Be Faster Pertaining to Lover clubs, gaming communities, And even diehards. Nor, Would you give up will have to Examine Totally with regards to Some outspoken As wll as outrageous experts either. Indeed, a few of their toughest you can find Plus most challenging experts prove to Tend to be one of the best untrained Resource able to mankind. That could be right, Which could cause trainers Within game, Discussed that happen to be Desktop pc gaming addicts, Some kind of Possibly go to self-proclaimed, are fresh For many Imminent gaming software designers, As well consultants.

After all, in a Firm Great Acquire Your home business Nicer You ought to for customers, And as well Fascinatingly enough, Harmful Buyers of internet based Turmoil will be more university grateful to Produce Your opinions, Ideas And also Find out program code and offer animation. It?s always unbelievable Methods Harmful Free gamers take Those Exercises Significantly Further than What exactly Virtually any Most recent originators may even imagine. Indeed, members of Gaming Communities what Genuinely Best Video Game Designers, In fact it is Most probably wicked Via the tap Into Ingenious spirit.

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Source: http://www.whatiscommunication.net/communication-skill/members-of-gaming-communities-are-the-best-video-game-designers-tap-into-innovation.html

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